MHRA Press Release on weight loss drugs!

On 5th June 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) issued a press release to remind women with diabetes also taking the popular medicines for weight loss to use safe and effective contraception. In some cases, it is advised that women stop the medication at least two months before trying to get pregnant.

The GLP-1 medicines brand names include Ozempic, Mounjaro, Wegovy, Saxenda and Victoza and the key points are:

  • They should not be taken during pregnancy, while trying to get pregnant, or during breastfeeding.
  • Anyone who gets pregnant while using them should speak to their healthcare professional and stop the medicine as soon as possible. This is because there is not enough safety data to know whether taking the medicine could cause harm to the baby.
  • Women taking Mounjaro, who are overweight and using an oral form of contraception, are advised to also use a non-oral form (the implant, coil or condoms). Mounjaro may reduce the effectiveness of oral contraceptives in those who are overweight.

This advice is already in the patient leaflets that come with the medicine and is just one of the reminders in the latest guidance from the MHRA on the safe use of “GLP-1 medicines”. However, the UK regulator is concerned that some people are not using these medicines for weight loss safely.

The full advice can be found on the MHRA website: https://www.gov.uk/government/publications/glp-1-medicines-for-weight-loss-and-diabetes-what-you-need-to-know

Warnings!
On 5th June 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) issued a press release to remind women with diabetes also taking the popular medicines for weight loss to use safe and effective contraception. In some cases, it is advised that women stop the medication at least two months before trying to get pregnant.

The GLP-1 medicines brand names include Ozempic, Mounjaro, Wegovy, Saxenda and Victoza and the key points are:

  • Alongside advice on contraceptive use, the MHRA also reminds patients that these medicines should not be bought from unregulated sellers such as beauty salons, via social media or taken without a prior consultation with a healthcare professional. Not only does this expose people wanting to lose weight to serious health risks, it is also against the law to sell these medicines in this way. The only way to guarantee receiving a genuine GLP-1 medicine is to obtain it from a legitimate pharmacy.
  • The guidance also reminds patients of the symptoms to look out for in the event of acute pancreatitis which, although uncommon, can be serious. The main symptom of this is severe pain in the stomach that radiates to the back and doesn’t go away. Anyone who experiences this should seek immediate medical help.
  • Anyone who suspects that they’ve had an adverse reaction to a GLP-1 medicine or suspects it is not a genuine product, should report it to the MHRA Yellow Card scheme. https://yellowcard.mhra.gov.uk
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